April 21, 2025

The enteric nervous system: the guts hidden brain

Think the brain is the only control centre in your body? Think again. We often talk about gut health in terms of food and digestion—but there’s a powerful, lesser-known player involved in how your gut (and your entire body) functions: the enteric nervous system (ENS).

Known as the “second brain,” the ENS is a vast network of over 100 million neurons embedded in the walls of your gut. It can function independently of your brain, yet it stays in constant conversation with it. This communication happens through the gut-brain axis, primarily via the vagus nerve—and it has a profound influence on your mood, digestion, immune response, and how you cope with stress.

In this insightful blog for Healf, Natalie takes you through the essential role of the ENS—what it is, how it works, and why it matters. You’ll learn:

  • How the ENS regulates digestion, from peristalsis to enzyme release

  • Why 90% of serotonin (your “feel-good” neurotransmitter) is made in the gut

  • The impact of stress on gut function and how the ENS is directly involved

  • The connection between the ENS and conditions like IBS and gastroparesis

  • Lifestyle and nutritional therapies that can help restore balance and improve symptoms

You’ll also discover supplement recommendations to support the ENS—including Natalie’s top picks—and how mindfulness, movement, and a personalised approach to nutrition can calm this vital system and boost your well-being.

If you’ve been chasing solutions to gut issues, mood swings, or energy crashes, this could be the piece of the puzzle you’ve been missing.

Understanding your gut’s “second brain” might be the key to finally feeling like yourself again.

Read the full blog to explore the enteric nervous system and discover how to truly support it from the inside out.

Ready to calm your gut brain axis?

At Integral Wellness, we approach your health holistically, appreciating that no system of the body works in silo and nothing can be addressed that way either.

This is true healthcare and we're here to help. Book a completely free call to find out how you can resolve your health niggles, today.
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